Hsiang-Chi Huang, Iwona Nowak, Vivian Lobo, Danica F Besavilla, Karin Schön, Jakub O Westholm, Carola Fernandez, Angana AH Patel, Clotilde Wiel, Volkan I Sayin, Dimitrios G Anastasakis, Davide Angeletti, Aishe A Sarshad. Nuclear RNAi modulates Influenza A virus infectivity by downregulating type-I Interferon response. BioRxiv. doi: https://doi.org/10.1101/2024.03.07.583365
Vivian Lobo*, Iwona Nowak*, Carola Fernandez, Ana Iris Correa Muler, Jakub O Westholm, Hsiang-Chi Huang, Ivo Fabrik, Hang T Huynh, Evgeniia Shcherbinina, Melis Poyraz, Anetta Härtlova, Daniel Benhalevy, Davide Angeletti, Aishe A Sarshad#, Loss of Lamin A leads to the nuclear translocation of AGO2 and compromised RNA interference, Nucleic Acids Research, 2024;, gkae589, https://doi.org/10.1093/nar/gkae589. PMID: 38994560.
Miriam Cipullo, Genís Valentín Gesé, Shreekara Gopalakrishna, Annika Krueger, Vivian Lobo, Maria A Pirozhkova, James Marks, Petra Páleníková, Dmitrii Shiriaev, Yong Liu, Jelena Misic, Yu Cai, Minh Duc Nguyen, Abubakar Abdelbagi, Xinping Li, Michal Minczuk, Markus Hafner, Daniel Benhalevy, Aishe A Sarshad, Ilian Atanassov, B Martin Hällberg, Joanna Rorbach. GTPBP8 plays a role in mitoribosome formation in human mitochondria. Nature Communication 15, 5664 (2024). https://doi.org/10.1038/s41467-024-50011-x. PMID: 38969660
Vivian Lobo*, Evgeniia Shcherbinina*, Jakub O Westholm, Iwona Nowak, Hsiang-Chi Huang, Davide Angeletti, Dimitrios G Anastasakis, Aishe A Sarshad. Integrative transcriptomic and proteomic profiling of the effects of cell confluency on gene expression. Scientific Data 11, 617 (2024). https://doi.org/10.1038/s41597-024-03465-z. PMID: 38866801
Hang T Huynh*, Evgeniia Shcherbinina*, Hsiang‐Chi Huang, Reyhaneh Rezaei, Aishe A Sarshad. Biochemical Separation of Cytoplasmic and Nuclear Fraction for Downstream Molecular Analysis. Current Protocols. 2024 May;4(5):e1042. doi: 10.1002/cpz1.1042. PMID: 38767195.
Iwona Nowak and Aishe A Sarshad. Argonaute proteins take center stage in cancers. Cancers 2021, 13(4), 788; https://doi.org/10.3390/cancers13040788. PMID: 33668654
Stephan P Rosshart#, Jasmin Herz, Brian G Vassallo, Ashli Hunter, Morgan K Wall, Jonathan H Badger, John A McCulloch, Dimitrios G Anastasakis, Aishe A Sarshad, Irina Leonardi, Nicholas Collins, Joshua A Blatter, Seong-Ji Han, Samira Tamoutounour, Svetlana Potapova, Mark B Foster St. Claire, Wuxing Yuan, Shurjo K Sen, Matthew S Dreier, Benedikt Hild, Markus Hafner, David Wang, Iliyan D Iliev, Yasmine Belkaid, Giorgio Trinchieri, Barbara Rehermann# A natural microbiota-based mouse model with increased translational research value for immune diseases. Science. 2019 Aug 2;365(6452):eaaw4361. doi: 10.1126/science.aaw4361. PMID: 31371577
Bruna Rodrigues Muys, Josane F Sousa, Jessica Rodrigues Plaça, Luíza Ferreira de Araújo, Aishe A Sarshad, Dimitrios G Anastasakis, Xiantao Wang, Xiao Ling Li, Greice Andreotti de Molfetta, Anelisa Ramao, Ashish Lal, Daniel Onofre Vidal, Markus Hafner, Wilson A Silva. miR-450a acts as a tumor suppressor in ovarian cancer by regulating energy metabolism. Cancer Research. 2019 Jul 1;79(13):3294-3305. doi: 10.1158/0008-5472.CAN-19-0490. PMID: 31101765
Quan Q Gao, William E Putzbach, Andrea E Murmann, Siquan Chen, Aishe A Sarshad, Johannes M Peter, Elizabeth T Bartom, Markus Hafner, Marcus E Peter. 6mer seed toxicity in tumor suppressive microRNAs. Nature communications vol. 9,1 4504. 29 Oct. 2018, doi:10.1038/s41467-018-06526-1. PMID: 30374110
Will Putzbach*, Ashley Haluck-Kangas*, Quan Q Gao, Aishe A Sarshad, Elizabeth T Bartom, Austin Stults, Abdul S Qadir, Markus Hafner, Marcus E Peter CD95L mRNA is toxic to cells. Elife. 2018 Oct 16;7:e38621. doi: 10.7554/eLife.38621. PMID: 30324908
Aishe A Sarshad, Aster H Juan, Ana Iris Correa Muler, Dimitrios G Anastasakis, Xiantao Wang, Pavol Genzor, Xuesong Feng, Pei-Fang Tsai, Hong-Wei Sun, Astrid D Haase, Vittorio Sartorelli, Markus Hafner. Argonaute-miRNA complexes silence target mRNAs in the nucleus of mammalian stem cells. Molecular Cell.2018 Sep 20;71(6):1040-1050.e8. doi: 10.1016/j.molcel.2018.07.020. PMID: 30146314
Pei-Fang Tsai, Stefania Dell’Orso, Joseph Rodriguez, Karinna O Vivanco, Kyung-Dae Ko, Kan Jiang, Aster H Juan, Aishe A Sarshad, Laura Vian, Michelle Tran, Darawalee Wangsa, A Hongjun Wang, Jelena Perovanovic, Dimitrios Anastasakis, Evelyn Ralston, Thomas Ried, Hong-Wei Sun, Markus Hafner, Daniel R Larson, Vittorio Sartorelli. A Muscle Super-Enhancer RNA Mediates Cohesin Recruitment and Regulates Transcription in Trans. Molecular Cell. 2018 Jul 5;71(1):129-141.e8. doi: 10.1016/j.molcel.2018.06.008. PMID: 29979962
Daniel Benhalevy*, Hannah L McFarland*, Aishe A Sarshad*, Markus Hafner. PAR-CLIP and streamlined small RNA cDNA library preparation protocol for the identification of RNA binding protein target sites. Methods. 2017 Apr 15;118-119:41-49. doi: 10.1016/j.ymeth.2016.11.009. PMID: 27871973
William Putzbach, Quan Q Gao, Monal Patel, Stijn Van Dongen, Ashley Haluck-Kangas, Aishe A Sarshad, Elizabeth T Bartom, Kwang-Youn A Kim, Denise M Scholtens, Markus Hafner, Jonathan C Zhao, Andrea E Murmann, Marcus E Peter. Many si/shRNAs can kill cancer cells by targeting multiple survival genes through an off-target mechanism. Elife. 2017 Oct 24;6:e29702. doi: 10.7554/eLife.29702. PMID: 29063830.
Randall A Dass, Aishe A Sarshad, Brittany B Carson, Jennifer M Feenstra, Amanpreet Kaur, Ales Obrdlik, Matthew M Parks, Varsha Prakash, Damon K Love, Kristian Pietras, Rosa Serra, Scott C Blanchard, Piergiorgio Percipalle, Anthony MC Brown, C Theresa Vincent. Wnt5a Signals through DVL1 to Repress Ribosomal DNA Transcription by RNA Polymerase I. PLoS Genetics. 2016 Aug 8;12(8):e1006217. doi: 10.1371/journal.pgen.1006217. PMID: 27500936.
Tara Dutka*, Aishe A Sarshad*, Markus Hafner. PAR-CLIP: A Genomic Technique to Dissect RNA-Protein Interactions. Field Guidelines for Genetic Experimental Designs in High-Throughput Sequencing (2016) pp 261-289. Doi 10.1007/978-3-319-31350-4
Bader Almuzzaini, Aishe A Sarshad, Aldwin S Rahmanto, Magnus L Hansson, Anne Von Euler, Olle Sangfelt, Neus Visa, Ann‐Kristin Östlund Farrants, Piergiorgio Percipalle. In β-actin knockouts, epigenetic reprogramming and rDNA transcription inactivation lead to growth and proliferation defects. FASEB Journal. 2016 Aug;30(8):2860-73. doi: 10.1096/fj.201600280R. PMID: 27127100.
Bader Almuzzaini, Aishe A Sarshad, Ann-Kristin Östlund Farrants, Piergiorgio Percipalle. Nuclear myosin 1 contributes to a chromatin landscape compatible with RNA polymerase II transcription activation. BMC Biol. 2015 Jun 5;13:35. doi: 10.1186/s12915-015-0147-z. PMID: 26044184
Aishe A Sarshad, Martin Corcoran, Bader Al-Muzzaini, Laura Borgonovo-Brandter, Anne Von Euler, Douglas Lamont, Neus Visa, Piergiorgio Percipalle. Glycogen synthase kinase (GSK) 3β phosphorylates and protects nuclear myosin 1c from proteasome-mediated degradation toactivate rDNA transcription in early G1 cells. PLoS Genetics. 2014 Jun 5;10(6):e1004390. doi: 10.1371/journal.pgen.1004390. PMID: 24901984.
Aishe A Sarshad and Piergiorgio Percipalle. New insight into role of myosin motors for activation of RNA polymerases. Int Rev Cell Mol Biol. 2014;311:183-230. doi: 10.1016/B978-0-12-800179-0.00004-0. PMID: 24952918.
Aishe Sarshad*, Fatemeh Sadeghifar*, Emilie Louvet*, Raffaele Mori, Stefanie Böhm, Bader Al-Muzzaini, Anna Vintermist, Nathalie Fomproix, Ann-Kristin Östlund, Piergiorgio Percipalle Nuclear Myosin 1c Facilitates the Chromatin Modifications Required to Activate rRNA Gene Transcription and Cell Cycle Progression. PLoS Genetics. 2013 Mar;9(3):e1003397. doi: 10.1371/journal.pgen.1003397. Epub 2013 Mar 21. PMID: 23555303.
